ResearchHow does spontaneous reorganization of brain activity allow us to adaptively change our behavior? That is, numerous neurons in our brain have to coordinate their activities to let us behave adaptively, similar to musicians in an orchestra. In contrast to the orchestra, the brain does not have a conductor. Using the mathematical framework of dynamical systems, we will map mechanisms of self-organization and change in a combined experimental and computational approach.
This project is funded by the The Netherlands Organisation for Scientific Research (NWO) through the Innovational Research Incentives Scheme Veni and carried out in collaboration with Andreas Daffertshofer and the Systems Neuroscience Group in Sydney, Australia.
Mehrkanoon S, Breakspear M, Boonstra TW (2014). The reorganization of corticomuscular coherence during a transition between sensorimotor states. NeuroImage, in press.
Van de Steeg C, Daffertshofer A, Stegeman DF, Boonstra TW (2014). High-density surface electromyography improves the identification of oscillatory synaptic inputs to motor neurons. Journal of Applied Physiology 116: 1263-1271.
Heitmann, S, Boonstra TW, Breakspear M (2013). A dendritic mechanism for decoding traveling waves: Principles and applications to motor cortex. PLoS Computational Biology9: e1003260.
Boonstra TW and Breakspear M (2012). Neural mechanisms of intermuscular coherence: Implications for the rectification of surface electromyography. Journal of Neurophysiology 107: 796-807.
Boonstra TW, Daffertshofer A, Roerdink M, Flipse I, Groenewoud K and Beek PJ (2009). Bilateral motor unit synchronization of leg muscles during a simple dynamic balance task. European Journal of Neuroscience 29: 613-622.
Boonstra TW, Daffertshofer A, van Ditshuizen JC, van den Heuvel MRC, Hofman C, Willigenburg NW and Beek PJ (2008). Fatigue-related changes in motor-unit synchronization of quadriceps muscles within and across legs. Journal of Electromyography and Kinesiology 18(5): 717-731.
Boonstra TW, Daffertshofer A, Breakspear M and Beek PJ (2007). Multivariate time-frequency analysis of electromagnetic brain activity during bimanual motor learning. NeuroImage 36(2): 370-377.